Kids With Food Allergies
 home   
what's new recipes resources allergy alerts find friends
donate shop KFA allergy buyer's guide support forums
  membership   site map     contact us   about   

Food Allergy Resources

Current Clinical Trial Studies Involving Food Allergy

October 2011



National Institutes of Health (NIH)

Food Allergy Studies - Clinical Trial List

These studies are registered with the National Institutes of Health (as of October 29, 2011) and involve investigation of food allergy, food hypersensitivity, eosinophilic disorders, anaphylaxis, asthma, eczema, gastrointestinal disorders, and other food allergy-related atopic disease.

See our related resources for information on clinical studies specifically for peanut allergy, milk allergy or egg allergy.

Study 1:
Title: Sublingual Immunotherapy for Food Allergy
Recruitment: Active, not recruiting
Study Results: No Results Available
Conditions: Food Allergies
Interventions: Other: Food Drops: Food Allergens (peptides)
Sponsors: University of Missouri-Columbia
Gender: Both
Age Groups: Child | Adult | Senior
Phases:
Start Date: October 2008
Completion Date: October 2010
Primary Completion Date: October 2009
Outcome Measures: Validated Questionnaires will be administered to trial participants at 3, 6, 9, 12 months after achieving the maintenance dose of food drops.
URL: http://ClinicalTrials.gov/show/NCT00736281

Study 2:
Title: Food Allergy - Tubes - Adenoids (FATA) Trial
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Otitis Media With Effusion | Food Hypersensitivity
Interventions: Other: Food Allergy Diagnosis | Procedure: Adenoidectomy
Sponsors: University of Missouri-Columbia
Gender: Both
Age Groups: Child
Phases:
Start Date: October 2008
Completion Date: October 2010
Acronym: FATA
Primary Completion Date: October 2009
Outcome Measures: The number of post-op ROM episodes in each group (1,2,3) will be recorded throughout the study (after the tympanostomy tubes fall out).
URL: http://ClinicalTrials.gov/show/NCT00736112

Study 3:
Title: Therapeutic Effect of Chinese Herbal Medicine on Food Allergy
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Allergy
Interventions: Drug: FAHF-2 (TM)
Sponsors: Li, Xiu-Min, M.D. | National Center for Complementary and Alternative Medicine (NCCAM)
Gender: Both
Age Groups: Child | Adult
Phases: Phase II
Start Date: December 2007
Completion Date: June 2012
Last Updated: November 3, 2010
Last Verified: November 2010
Acronym: FAHF-2
Primary Completion Date: May 2012
Outcome Measures: Safety of FAHF-2|lab studies
URL: http://ClinicalTrials.gov/show/NCT00602160

Study 4:
Title: Adherence to Self-care Regimens for Young People With Food Allergy
Recruitment: Completed
Study Results: No Results Available
Conditions: Food Allergy
Interventions:
Sponsors: Brighton & Sussex Medical School | Brighton and Sussex University Hospitals NHS Trust|Guy's & St Thomas' NHS Foundation Trust
Gender: Both
Age Groups: Child | Adult
Phases:
Start Date: January 2010
Completion Date: March 2011
Primary Completion Date: March 2011
Outcome Measures: Self-reported adherence to self-care regimens of adolescents and young adults with food allergy
URL: http://ClinicalTrials.gov/show/NCT01006382

Study 5:
Title: Immunopathogenesis of Food Allergy and Eosinophilic Gastrointestinal Disorders
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Hypersensitivity | Eosinophilia | Peanut Hypersensitivity
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)
Gender: Both
Age Groups: Adult
Phases:
Start Date: August 2010
Completion Date:
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT01212016

Study 6:
Title: Atopy Patch Test in Children With Food Allergy-related Gastrointestinal Symptoms
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Allergy
Interventions: Device: Atopy patch test with food allergen
Sponsors: Mahidol University
Gender: Both
Age Groups: Child | Adult
Phases: Phase I
Start Date: April 2010
Completion Date: March 2011
Acronym: APT
Primary Completion Date: December 2010
Outcome Measures: Prevalence of positive reaction in APT in children with food allergy-related gastrointestinal symptoms | Comparisons atopy patch test reaction between lyophilized allergen and commercial allergen
URL: http://ClinicalTrials.gov/show/NCT01164293

Study 7:
Title: Endomicroscopy in Patients With Food Allergy: a New Diagnostic Option
Recruitment: Not yet recruiting
Study Results: No Results Available
Conditions: Food Allergy
Interventions:
Sponsors: University of Erlangen-Nürnberg Medical School
Gender: Both
Age Groups: Adult | Senior
Start Date: February 2010
Completion Date: June 2013
Primary Completion Date: December 2012
Outcome Measures: The degree of oedema formation, the amount of cell infiltration and the expansion of lymph nodes.
URL: http://ClinicalTrials.gov/show/NCT01072084

Study 8:
Title: An Observational Study of Childhood Food Allergy
Recruitment: Active, not recruiting
Study Results: No Results Available
Conditions: Food Hypersensitivity | Peanut Hypersensitivity | Egg Hypersensitivity | Milk Hypersensitivity
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)|Consortium of Food Allergy Research
Gender: Both
Age Groups: Child
Phases:
First Received: July 21, 2006
Start Date: July 2006
Completion Date: July 2016
Primary Completion Date: July 2016
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT00356174

Study 9:
Title: Quality of Life in Food Allergic Families
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Allergy
Interventions: Behavioral: Counseling
Sponsors: University of Michigan
Gender: Both
Age Groups: Child
Start Date: January 2010
Completion Date: July 2011
Primary Completion Date: July 2011
Outcome Measures: Difference in validated quality of life survey
URL: http://ClinicalTrials.gov/show/NCT01054950

Study 10:
Title: Evaluation of Food Hypersensitivity in Children/Adolescents With Functional Dyspepsia
Recruitment: Completed
Study Results: http://www.ncbi.nlm.nih.gov/pubmed/20216101?dopt=Abstract
Conditions: Dyspepsia
Interventions: Device: in vitro and in vivo allergy testing
Sponsors: Children's Mercy Hospital Kansas City
Gender: Both
Age Groups: Child
Phases: Phase I
Start Date: June 2006
Completion Date: September 2008
Primary Completion Date: September 2008
Outcome Measures: measure specific IgE, IgG total, IgG subclass 4, skin prick tests and atopy patch tests to milk, egg, soy, corn, peanut and wheat | Determine T-lymphocytes, eosinophils and mast cell densities on duodenal biopsy samples demonstrating eosinophilia
URL: http://ClinicalTrials.gov/show/NCT00328679

Study 11:
Title: Analysis of Immunological Reactions to Foods in Birch Pollen-Allergic Patients
Recruitment: Not yet recruiting
Study Results: No Results Available
Conditions: Allergic Rhinitis | Food Allergy
Interventions:
Sponsors: Medical University of Vienna
Gender: Both
Age Groups: Adult
Start Date: December 2008
Completion Date: December 2010
Acronym:
Primary Completion Date: January 2010
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT00787631


Study 12:
Title: Bacille Calmette-Guérin (BCG) Vaccine and Atopy
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Asthma | Eczema | Food Hypersensitivity
Interventions:
Sponsors: Bandim Health Project|Murdoch Childrens Research Institute
Gender: Both
Age Groups: Child
Start Date: October 2011
Completion Date: October 2012
Primary Completion Date: October 2012
Outcome Measures: Skin prick test | Symptoms of asthma | Symptoms of eczema | Symptoms of food allergy
URL: http://ClinicalTrials.gov/show/NCT01420705

Study 13:
Title: The Diagnosis of Oral Allergy Syndrome Through the Use of a Structured Questionnaire
Recruitment: Completed
Study Results: No Results Available
Conditions: Food Allergy
Interventions:
Sponsors: Royal Brompton & Harefield NHS Foundation Trust
Gender: Both
Age Groups: Adult | Senior
Phases:
Start Date: May 2005
Completion Date: September 2007
Primary Completion Date: September 2006
Outcome Measures: The validation of the OAS diagnostic questionnaire (PFSDQ) against accepted standard methods of diagnosis. | The characterisation of the pollen and aeroallergen sensitivities of those diagnosed with roal allergy syndrome
URL: http://ClinicalTrials.gov/show/NCT00854958


Study 14:
Title: Efficacy Study of Montelukast in Atopic Dermatitis Induced by Food Allergens
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Atopic Dermatitis
Interventions: Drug: Montelukast|Drug: Placebo
Sponsors: 1st Allergy & Clinical Research Center | Merck
Gender: Both
Age Groups: Child
Phases: Phase IV
Start Date: November 2007
Completion Date: March 2008
Primary Completion Date:
Outcome Measures: The change in validated skin assessment scores (EASI) in treating symptoms of atopic dermatitis associated with food allergens|The change in serum and urinary inflammatory marker levels|The change in GRSR validated scale for treating gastrointestinal symptoms induced by food allergens
URL: http://ClinicalTrials.gov/show/NCT00557284


Study 15:
Title: Data and Sample Collection Study to Elucidate the Mechanisms of Eosinophilic Disorders
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Eosinophilic Gastrointestinal Disease Eosinophilic Inflammatory Disease | Food Allergy
Interventions:
Sponsors: Children's Hospital Medical Center, Cincinnati | Rothenberg, Marc E., M.D., Ph.D.
Gender: Both
Age Groups: Child | Adult
Phases:
Start Date: May 2005
Completion Date:
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT00267501


Study 16:
Title: Asthma, a Disease Due to a Lack of Bacterial Infections in Childhood.
Recruitment: Completed
Study Results: No Results Available
Conditions: Food Allergy | Atopic Dermatitis | Asthma | Rhinitis
Interventions: Biological: BCG
Sponsors: The Netherlands Asthma Foundation
Gender: Both
Age Groups: Child | Adult | Senior
Start Date: January 1999
Completion Date: July 2005
Primary Completion Date:
Outcome Measures: Incidence and severity of atopic disease. | SCORAD, lung function, IgE, cytokine production by PBMNC's, NRAMP-polymorphisms.
URL: http://ClinicalTrials.gov/show/NCT00200928


Study 17:
Title: Primary Prevention of Atopic Disease by Perinatal Administration of Probiotics
Recruitment: Completed
Study Results: No Results Available
Conditions: Food Allergy | Atopic Dermatitis | Asthma | Rhinitis
Interventions: Dietary Supplement: Probiotic bacteria | Dietary Supplement: Placebo
Sponsors: The Netherlands Asthma Foundation | UMC Utrecht
Gender: Both
Age Groups: Adult
Completion Date: August 2008
Primary Completion Date: December 2007
Outcome Measures: Incidence and severity of atopic disease at the age of 2 years. Incidence and prevalence of eczema | Serum IgE, stool composition, cytokines produced by PBMNC's
URL: http://ClinicalTrials.gov/show/NCT00200954


Study 18:
Title: Role of Recombinants in Peach Allergy
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Allergy
Interventions:
Sponsors: Niguarda Hospital
Gender: Both
Age Groups: Adult | Senior
Phases:
Start Date: July 2008
Completion Date: November 2010
Primary Completion Date: October 2009
Outcome Measures: Evaluation of diagnostic efficacy of PHADIA IMMUNO-CAP with the peach recombinant allergens Pru p 3, 1 and 4 as compared to peach IMMUNO-CAP in the identification of peach allergic subjects at major risk of anaphylaxis. | Evaluate whether the above recombinants allergens could help identifying subjects with severe reaction to other fruits
URL: http://ClinicalTrials.gov/show/NCT00715156


Study 19:
Title: Use of Hypoallergenic (H.A.) Cereals in Children With Diagnosed Allergy to Wheat
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Allergy
Interventions: Other: HA wheat cereals
Sponsors: Nestlé Nutrition Corporate
Gender: Both
Age Groups: Child
Phases:
Start Date: April 2011
Completion Date: August 2012
Primary Completion Date: February 2012
Outcome Measures: Specific Oral Tolerance Induction (SOTI) with hypoallergenic wheat in children allergic to wheat|assess allergic reactions to a challenge test to wheat
URL: http://ClinicalTrials.gov/show/NCT01332084


Study 20:
Title: Extensively Hydrolyzed Formula: Hypoallergenicity
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Food Hypersensitivity
Interventions: Other: Extensively hydrolyzed, whey protein infant formula|Other: Extensively hydrolyzed, casein protein infant formula
Sponsors: Nestlé Nutrition Corporate
Gender: Both
Age Groups: Child
Start Date: February 2011
Completion Date: April 2012
Primary Completion Date: February 2012
Outcome Measures: Hypoallergenicity | Digestive Tolerance
URL: http://ClinicalTrials.gov/show/NCT01278446


Study 21:
Title: A Study to Assess the Role of a Gluten Free-dairy Free (GFCF) Diet in the Dietary Management of Autism Associated Gastrointestinal Disorders
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Autism | Gastrointestinal Symptoms
Interventions: Other: GFCF product with GFCF diet | Other: product containing gluten and casein (milk protein) with GFCF diet
Sponsors: Massachusetts General Hospital | Nutricia North America
Gender: Both
Age Groups: Child
Start Date: April 2010
Completion Date: April 2011
Acronym: GFCF
Primary Completion Date: April 2011
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT01116388

Study 22:
Title: Clinical and Immunological Evaluation of Children With Allergies
Recruitment: Completed
Study Results: No Results Available
Conditions: Hypersensitivity, Immediate
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)
Gender: Both
Age Groups: Child | Adult
Phases:
Start Date: January 2005
Completion Date: August 2010
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT00102570

 

Study 23:
Title: Sublingual Immunotherapy of Birch Pollen Associated Apple Allergy
Recruitment: Not yet recruiting
Study Results: No Results Available
Conditions: Birch Pollen Related Apple Allergy | Birch Pollen Allergy
Interventions: Drug: rMal d 1 | Drug: rBet v 1 | Other: placebo drops
Sponsors: Medical University of Vienna | Austrian Science Fund (FWF)
Gender: Both
Age Groups: Adult
Phases: Phase II
Start Date: December 2011
Completion Date: January 2014
Primary Completion Date: January 2013
Outcome Measures: allergen concentration to induce allergic reactions in the oral cavity as a measure of efficacy (oral provocation test). | T cell proliferation and cytokine production as a measure of tolerance induction
URL: http://ClinicalTrials.gov/show/NCT01449786

Study 24:
Title: Natural History of Diseases Associated With Allergic Inflammation: Atopic Dermatitis and Genetic and Congenital Diseases Associated With Atopic Pathways
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Atopic Dermatitis | Netheron's Syndrome | Piebaldism | Hyper IgE Syndrome | Ichthyosis | Anaphylaxis | Severe Allergy
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)
Gender: Both
Age Groups: Child | Adult | Senior
Start Date: June 2010
Completion Date:
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT01164241


Study 25:
Title: A Long-Term Examination of Asthma From Childhood Through Adolescence
Recruitment: Active, not recruiting
Study Results: No Results Available
Conditions: Asthma | Dermatitis, Atopic | Rhinitis | Urticaria
Interventions:
Sponsors: National Heart, Lung, and Blood Institute (NHLBI)
Gender: Both
Age Groups: Child | Adult
Start Date: September 2007
Completion Date: May 2011
Primary Completion Date:
Outcome Measures: Identifying factors that may increase a person's chance of having recurrent asthma as an adult
URL: http://ClinicalTrials.gov/show/NCT00541255


Study 26:
Title: Promoting Tolerance to Common Allergens in High-Risk Children: Global Prevention of Asthma in Children (GPAC) Study
Recruitment: Active, not recruiting
Study Results: No Results Available
Conditions: Asthma | Allergic Rhinitis
Interventions: Biological: Oral mucosal immunoprevention (OMIP) therapy | Biological: Placebo
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) | Immune Tolerance Network (ITN)
Gender: Both
Age Groups: Child
Phases: Phase II
Start Date: May 2006
Completion Date: June 2013
Acronym: GPAC
Primary Completion Date: June 2013
Outcome Measures: Allergic sensitization in children at high risk of asthma and atopy. | Incidence of asthma in children at high risk for developing asthma and atopy. | Effects of OMIP on the immune response to allergens
URL: http://ClinicalTrials.gov/show/NCT00346398

Study 27:
Title: Influence of Probiotics on Atopy, Immunological Responses and Gut Microflora - Follow-up to 5 Years
Recruitment: Active, not recruiting
Study Results: No Results Available
Conditions: Eczema | Asthma | Allergic Rhinitis
Interventions: Dietary Supplement: Probiotic|Other: Placebo
Sponsors: National University Hospital, Singapore | National University, Singapore
Gender: Both
Age Groups: Child | Adult | Senior
Phases: Phase II
Start Date: May 2006
Completion Date:
Primary Completion Date: July 2011
Outcome Measures: Asthma | Atopic eczema | Allergic Rhinitis | Allergen sensitization | Food Allergy
URL: http://ClinicalTrials.gov/show/NCT00365469


Study 28:
Title: Allergy Immunotherapy for the Reduction of Asthma
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Wheezing | Asthma | Allergy
Interventions: Biological: Allergen extracts (subcutaneous injections) | Other: Standard of care
Sponsors: Albert Einstein College of Medicine of Yeshiva University | Jacobi Medical Center
Gender: Both
Age Groups: Child
Phases: Phase I | Phase II
Start Date: October 2008
Completion Date: October 2015
Acronym: AIR
Primary Completion Date: October 2015
Outcome Measures: Combined asthma symptom and asthma medication score|Prevention of new allergic sensitization as determined by blood and/or skin testing to a panel of 9 common environmental and 9 common food allergens. | Observe Frequency and Phenotype of T regulatory cells in response to immunotherapy
URL: http://ClinicalTrials.gov/show/NCT01028560

Study 29:
Title: Eosinophilic Esophagitis Databank
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Esophagitis | Eosinophilic Esophagitis
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Gender: Both
Age Groups: Child | Adult
Phases:
Start Date: April 2011
Completion Date: April 2016
Primary Completion Date: April 2016
Outcome Measures: Elucidate the genetic components of EoE, focusing on a candidate gene approach the TSLP/WDR36 locus and through GWAS analysis
URL: http://ClinicalTrials.gov/show/NCT01323803


Study 30:
Title: Evaluation and Long-Term Follow-Up of Patients With Allergic and Inflammatory Disorders
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Inflammatory Disorder
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)
Gender: Both
Age Groups: Child | Adult | Senior
Phases:
Start Date: August 1996
Completion Date:
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT00557895


Study 31:
Title: A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab
Recruitment: Completed
Study Results: No Results Available
Conditions: Esophagitis
Interventions: Drug: omalizumab | Drug: Placebo
Sponsors: University of Utah | Novartis Pharmaceuticals
Gender: Both
Age Groups: Child | Adult
Phases: Phase II
Start Date: November 2005
Completion Date: January 2010
Primary Completion Date: January 2010
Outcome Measures: To determine the efficacy of omalizumab as determined by a reduction in eosinophils per high power field. | To determine the effect of omalizumab on other clinical and histological parameters of EE including reducing the symptoms of EE measured by overall improvement in esophageal symptoms
URL: http://ClinicalTrials.gov/show/NCT00123630


Study 32:
Title: Fluticasone Versus Esomeprazole to Treat Eosinophilic Esophagitis
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Eosinophilic Esophagitis
Interventions: Drug: Swallowed fluticasone | Drug: Esomeprazole
Sponsors: Walter Reed Army Medical Center
Gender: Both
Age Groups: Adult | Senior
Start Date: April 2008
Completion Date:
Primary Completion Date: April 2010
Outcome Measures: Histologic resolution of esophageal eosinophilia defined as < 7 eosinophils/high power field in both the proximal and distal esophagus. | Resolution of dysphagia symptoms with therapy using a validated questionnaire. | Endoscopic resolution of EE findings following treatment.
URL: http://ClinicalTrials.gov/show/NCT00895817

Study 33:
Title: Mothers' Thoughts About What Their Children Eat
Recruitment: Active, not recruiting
Study Results: No Results Available
Conditions: Healthy Volunteers
Interventions:
Sponsors: National Human Genome Research Institute (NHGRI)
Gender: Female
Age Groups: Adult | Senior
Start Date: March 2010
Completion Date:
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT01087346


Study 34:
Title: Screening Protocol for Genetic Diseases of Mast Cell Homeostasis and Activation
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Piebaldism | Idiopathic Anaphylaxis | Allergy | Chronic Urticara | Angioedema
Interventions:
Sponsors: National Institute of Allergy and Infectious Diseases (NIAID)
Gender: Both
Age Groups: Child | Adult | Senior
Start Date: February 2009
Completion Date:
Primary Completion Date:
Outcome Measures:
URL: http://ClinicalTrials.gov/show/NCT00852943

Study 35:
Title: Accuracy Of Skin Prick Test Using In-house Wheat Extract For The Diagnosis Of IgE-mediated Wheat Allergy: A Pilot Study
Recruitment: Recruiting
Study Results: No Results Available
Conditions: Wheat Allergy
Interventions: Other: Commercial extract and in-house wheat extract
Sponsors: Mahidol University
Gender: Both
Age Groups: Child
Start Date: June 2009
Completion Date: July 2010
Acronym:
Primary Completion Date: June 2010
Outcome Measures: correlation skin test result and food challenge result | Comparison of skin test result and specific IgE to challenge result
URL: http://ClinicalTrials.gov/show/NCT01070368

 

References:
U.S. National Institutes of Health. (October 29, 2011). Clinical Trials. Retrieved October 29, 2011 from http://www.clinicaltrials.gov/.





Kids With Food Allergies is a nonprofit charity. More than 80% of KFA's financial support comes from donors like you. If KFA has helped you in some way, please make a donation to support our work.

Page last updated 7/29/2012

We improve the day-to-day lives of families raising children with food allergies
and empower them to create a safe and healthy future for their children.

Memberships Support Forums Allergy-Free Recipes Allergy Education Resources Friends Connection
Food Allergy Alerts Donate Shop KFA Allergy Buyer's Guide Contact Us Press | Media

Privacy Policy and Terms of Service
Copyright (c) 2005-2011, Kids With Food Allergies, Inc. All Rights Reserved.
Kids With Food Allergies is a tax exempt charity.